![]() ![]() Quarantine along with others can also halve the reproductive number and reduce the incidence, thus, shortening the epidemic period effectively. Model estimates indicated that quarantine of exposed people averted 44 to 81% of incident cases and 31 to 63% of deaths. The studies consistently reported the benefit of quarantine, contact tracing, screening, and isolation in different settings. We included 22 (9 observational and 13 modeling) studies. The findings were presented narratively and in tabular form. Two experts screened the articles and assessed risk of bias with ROBINS-I tool and certainty of evidence with GRADE approach. Non-randomized and modeling articles published to date in areas of COVID prevention with contact tracing, screening, quarantine, and isolation were included. ![]() We conducted a systematic review in accordance with the PRISMA and Cochrane guidelines by searching articles from major medical databases such as PubMed/Medline, Global Health Database, Embase, CINAHL, Google Scholar, and clinical trial registries. Therefore, this study aimed to review evidences related to COVID-19 prevention strategies achieved through contact tracing, screening, quarantine, and isolation to determine best practices. However, there is no conclusive evidence. Some studies assessing the effects of different preventive strategies have been published. There is no proven effective treatment yet, except certain preventive mechanisms. It caused an extensive health and economic burden around the globe. COVID-19 is an emerging disease caused by highly contagious virus called SARS-CoV-2. ![]()
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